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The patient should be cautioned about concomitant use of alcohol or other CNS-active drugs and Diethylpropion hydrochloride. (See WARNINGS.) Thepatient should be advised to observe caution when driving or engaging in any potentially hazardous activity..
Central Nervous System: In a few epileptics an increase in convulsive episodes has been reported; rarely psychotic episodes at recommended doses;dyskinesia, blurred vision, overstimulation, nervousness, restlessness, dizziness, jitteriness, insomnia, anxiety, euphoria, depression, dysphoria,tremor, mydriasis, drowsiness, malaise, headache, and cerebrovascular accident.. Adipex-p vendita senza ricetta.
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This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impairedrenal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may beuseful to monitor renal function..
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Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics." It has not been established, however, that the action ofsuch drugs in treating obesity is primarily one of appetite suppression. For example, other central nervous system actions or metabolic effects may beinvolved. Adult obese subjects instructed in dietary management and treated with "anorectic" drugs lose more weight on the average than those treatedwith placebo and diet, as determined in relatively short-term clinical trials. The magnitude of increased weight loss of drug-treated patients overplacebo-treated patients averages some fraction of a pound a week. However, individual weight loss may vary substantially from patient to patient. Therate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks. Thepossible origins of the increased weight loss due to the various drug effects are not established. The amount of weight loss associated with the useof an "anorectic" drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugprescribed, such as the physician/investigator relationship, the population treated, and the diet prescribed. Studies do not permit conclusions as tothe relative importance of the drug and non-drug factors on weight loss..adipex-p vendita.
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Abuse with Diethylpropion hydrochloride during pregnancy may result in withdrawal symptoms in the human neonate..
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Since safety and effectiveness in pediatric patients below the age of 16 have not been established, Diethylpropion hydrochloride is not recommendedfor use in pediatric patients 16 years of age and under..
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Diethylpropion hydrochloride is a schedule IV controlled substance. Diethylpropion hydrochloride has some chemical and pharmacologic similarities tothe amphetamines and other related stimulant drugs that have been extensively abused. There have been reports of subjects becoming psychologicallydependent on Diethylpropion. The possibility of abuse should be kept in mind when evaluating the desirability of including a drug as part of a weightreduction program. Abuse of amphetamines and related drugs may be associated with varying degrees of psychologic dependence and social dysfunctionwhich, in the case of certain drugs, may be severe. There are reports of patients who have increased the dosage to many times that recommended. Abruptcessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG.Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity, and personalitychanges. The most severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia..
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Cardiovascular: Precordial pain, arrhythmia (including ventricular), ECG changes, tachycardia, elevation of blood pressure, palpitation and rarereports of pulmonary hypertension. Valvular heart disease associated with the use of some anorectic agents such as fenfluramine and dexfenfluramine,both independently and especially when used in combination, have been reported. Valvulopathy has been very rarely reported with Diethylpropionhydrochloride monotherapy, but the causal relationship remains uncertain.. adipex-p vendita senza ricetta.
Diethylpropion hydrochloride should not be used in combination with other anorectic agents, including prescribed drugs, over-the-counter preparations,and herbal products..
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