Posted on June 8, 2016
abilify maintena italia
Read expert perspectives on popular health topics. Abilify maintena italia.
This site contains information on the efficacy and safety profile of Abilify Maintena. It is intended for healthcare professionals only.
Abilify maintena italia - Lee mas
Descrizione abilify maintena italia
Although pathological gambling is listed as a reported side effect in the current aripiprazole drug labels, this description does not entirely reflectthe nature of the impulse-control risk FDA identified. In addition, FDA has become aware of other compulsive behaviors associated with aripiprazole,such as compulsive eating, shopping, and sexual actions. These compulsive behaviors can affect anyone who is taking the medicine. As a result, FDA isadding new warnings about all of these compulsive behaviors to the drug labels and the patient Medication Guides for all aripiprazole products.
In pregnant rabbits treated with oral doses of 10, 30, and 100 mg/kg/day which are 2 to 11 times human exposure at the oral MRHD based on AUC and 6 to65 times the oral MRHD of aripiprazole on mg/m2 basis during the period of organogenesis, decreased maternal food consumption and increased abortionswere seen at the highest dose as well as increased fetal mortality. Decreased fetal weight and increased incidence of fused sternebrae were observedat 3 and 11 times the MRHD based on AUC. Abilify maintena italia user .
Abilify Maintena®. See Important Safety & Full Prescribing Info, including Boxed WARNING for increased risk of death in some elderly patients.
Safety Database of Abilify Maintena and Oral Aripiprazole
Investigations:infrequent - blood creatine phosphokinase increased, blood pressure decreased, hepatic enzyme increased, liver function test abnormal,electrocardiogram QT-prolonged, rare - blood triglycerides decreased, blood cholesterol decreased, electrocardiogram T-wave abnormal Abilify maintena italia.
The key secondary efficacy endpoint, percentage of subjects meeting the relapse criteria, was statistically significantly lower in patients randomizedto the Abilify Maintena group (10%) than in the placebo group (40%).
Abilify maintena italia Otsuka Pharmaceutical Co., Ltd. is a global healthcare company with the corporate philosophy: ‘Otsuka- people creating new products for betterhealth worldwide'. Otsuka researches, develops, manufactures and markets innovative and original products, with a focus on pharmaceutical products forthe treatment of diseases and nutraceutical products for the maintenance of everyday health. .
Certain assumptions made by Lundbeck are required by Danish Securities Law for full disclosure of material corporate information. Some assumptions,including assumptions relating to sales associated with product that is prescribed for unapproved uses, are made taking into account past performancesof other similar drugs for similar disease states or past performance of the same drug in other regions where the product is currently marketed. It isimportant to note that although physicians may, as part of their freedom to practice medicine in the US, prescribe approved drugs for any use theydeem appropriate, including unapproved uses, at Lundbeck, promotion of unapproved uses is strictly prohibited.
Use appropriate aseptic techniques throughout injection procedure. For deep intramuscular injection only.abilify maintena italia.
Ricetta abilify maintena italia
Common adverse reactions (reported in at least 5% of all overdose cases) reported with oral aripiprazole overdosage (alone or in combination withother substances) include vomiting, somnolence, and tremor. Other clinically important signs and symptoms observed in one or more patients witharipiprazole overdoses (alone or with other substances) include acidosis, aggression, aspartate aminotransferase increased, atrial fibrillation,bradycardia, coma, confusional state, convulsion, blood creatine phosphokinase increased, depressed level of consciousness, hypertension, hypokalemia,hypotension, lethargy, loss of consciousness, QRS complex prolonged, QT prolonged, pneumonia aspiration, respiratory arrest, status epilepticus, andtachycardia. Abilify maintena italia.
Nervous System Disorders:infrequent - cogwheel rigidity, extrapyramidal disorder, hypersomnia, lethargy, rare- bradykinesia, convulsion, dysgeusia,memory impairment, oromandibular dystonia
Abilify maintena italia Avoid use of Abilify Maintena in combination with carbamazepine and other inducers of CYP3A4 for greater than 14 days [see DOSAGE ANDADMINISTRATION (2.3)]. .
abilify maintena italia.The most common side effect of Abilify Maintena includes feeling like you need to move to stop unpleasant feelings in your legs (restless leg syndromeor akathisia,) injection site pain, or sleepiness (sedation).
Our approximately 6,000 employees in 57 countries are engaged in the entire value chain throughout research, development, production, marketing andsales. Our pipeline consists of several late-stage development programmes and our products are available in more 100 countries. We have researchcentres in China, Denmark and the United States and production facilities in China, Denmark, France and Italy. Lundbeck generated revenue ofapproximately DKK15.3 billion in 2013 (EUR2.1 billion; USD2.7 billion).
The most common side effects with Abilify Maintena (which may 5 or more people in 100) are increased weight, akathisia (a constant urge to move),insomnia (difficulty sleeping) and injection site pain. For the full list of all side effects reported with Abilify Maintena, see the package leaflet. Abilify maintena italia.
Neonates exposed to antipsychotic drugs, including Abilify Maintena, during the third trimester of pregnancy are at risk for extrapyramidal and/orwithdrawal symptoms. There are insufficient data with Abilify Maintena use in pregnant women to inform a drug-associated risk. In animal reproductionstudies, oral and intravenous aripiprazole administration during organogenesis in rats and/or rabbits at doses 10 and 11 times, respectively, themaximum recommended human dose (MRHD) produced fetal death, decreased fetal weight, undescended testicles, delayed skeletal ossification, skeletalabnormalities, and diaphragmatic hernia. Oral and intravenous aripiprazole administration during the pre- and post-natal period in rats at doses 10times the maximum recommended human dose (MRHD) produced prolonged gestation, stillbirths, decreased pup weight, and decreased pup survival. Considerthe benefits and risks of Abilify Maintena and possible risks to the fetus when prescribing Abilify Maintena to a pregnant woman. Advise pregnantwomen of potential fetal risk. abilify maintena italia user
Video abilify maintena italia
Call your healthcare provider or go to the nearest emergency room right away if you have any of these symptoms.
Abilify Maintena (aripiprazole) - given as a depot injection - is one of key products Lundbeck needs to replace sales of Cipralex (escitalopram) andthe immediate-release oral formulation of Abilify that have been lost to generic competition. abilify maintena italia user .
Lay out and confirm that components listed below are provided in the kit:
The intensity of sedation was greater with the combination of oral aripiprazole and lorazepam as compared to that observed with aripiprazole alone.The orthostatic hypotension observed was greater with the combination as compared to that observed with lorazepam alone [see WARNINGS AND PRECAUTIONS(5.7)]. abilify maintena italia user .
Counsel patients about a potentially fatal adverse reaction referred to as NMS that has been reported in association with administration ofantipsychotic drugs. Advise patients, family members, or caregivers to contact a health care provider or report to the emergency room if theyexperience signs and symptoms of NMS [see WARNINGS AND PRECAUTIONS (5.3)].
To enter, please fill in the fields or select from an option below. , , .